Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury

ABSTRACT: Here we demonstrate that the neurovasculature exhibits a unique transcriptional signature following inflammatory insults, and pharmacological inhibition of monoacylglycerol lipase using a newly characterized inhibitor, rescues the transcriptional profile of brain vasculature, and restores its functional homeostasis.

ORGANISM(S): Mus musculus

PROVIDER: GSE113855 | GEO | 2018/05/10

REPOSITORIES: GEO