Transcriptome profiling of light-induced gene expression in the suprachiasmatic nucleus of T7 and T24 cycle-housed mice

ABSTRACT: To investigate changes in SCN photic responsiveness after exposure to an ultradian light cycle (T7 cycle; alternating 3.5-hour periods of light and darkness), we performed RNA-sequencing on isolated SCN samples obtained from T24 and T7 light cycle-housed mice that received a light pulse during their active phases. Our results indicate that the SCN becomes refractory to light induction of immediate-early gene expression after exposure to the T7 light cycle.

ORGANISM(S): Mus musculus

PROVIDER: GSE113875 | GEO | 2018/09/14

REPOSITORIES: GEO