The response of the hypothalamus to leptin and a high-fat diet in mice

ABSTRACT: Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. We have used a microarray-based transcriptomics approach to identify novel genes regulated by HFD and leptin in the hypothalamus using mouse global arrays.

ORGANISM(S): Mus musculus

PROVIDER: GSE113943 | GEO | 2018/09/30

REPOSITORIES: GEO