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The Polycomb Group protein Rnf2/Ring1b is essential for zebrafish development and cardiogenesis

ABSTRACT: Goal of the experiment was to assess the differences in gene expression between zygotic rnf2 mutant zebrafish embryos and wildtype embryos at 3 dpf. The goal of ChIP-sequencing of wildtype embryos at 3 dpf is to link deregulation in gene expression to the Rnf2 occupancy in the wildtype situation and check the overlap between Rnf2 and H3K27me3. The RNA-sequencing of single hearts was performed to assess differences in gene expression between zygotic rn2 mutants hearts and wildtype hearts at 3 different stages (1, 2, 3 dpf)

ORGANISM(S): Danio rerio

PROVIDER: GSE114038 | GEO | 2019/03/13

REPOSITORIES: GEO

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The Polycomb Group protein Rnf2/Ring1b is essential for zebrafish development and cardiogenesis

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