Discovery of a Drug Candidate for GLIS3-Associated Diabetes

ABSTRACT: Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation of TGF-beta signaling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE114051 | GEO | 2018/05/05

REPOSITORIES: GEO