Genomics

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JAG2 signaling induces differentiation of CD14+ monocytes into Langerhans Cell Histiocytosis-like cells


ABSTRACT: This study aims to identify the cell of origin of Langerhans Cell Histiocytosis and the molecular mechanisms of its pathogenesis. Overall design: Primary cells were isolated from peripheral blood (CD14 monocytes, CD1c DCs) and treated with JAG2, IgG or IL4 6 different conditions: CD14 and CD1c treated with IgG, JAG2 or IL4

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo Sapiens

SUBMITTER: Maximilian Kauer  

PROVIDER: GSE114181 | GEO | 2018-07-29

REPOSITORIES: GEO

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