Genomics

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Single cell profiling of human hematopoietic cells


ABSTRACT: We demonstrated that the induction of BAZ2B expression in human CD34+ cells or Lineage-CD34+CD38+ cells, enhanced the stemness of clonogenicity of the cells in in vitro assays. In order to confirm the stemness mRNA expression signature of the progenitors we performed single-cell sequencing of the BAZ2B-treated CD34+ or Lineage-CD34+CD38+ progenitors and used the luciferase-treated progenitors as a control.

ORGANISM(S): Homo sapiens

PROVIDER: GSE114239 | GEO | 2020/11/12

REPOSITORIES: GEO

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