Expression data from A549 human lung adenocarcinoma cells with and without knockdown against CNOT3

ABSTRACT: The physiological importance of mRNA degradation through the CCR4-NOT deadenylase has recently been highlighted. For example, mutation in CNOT3, a gene coding for sCNOT3 subunit of the CCR4-NOT complex, is found to be associated with T-cell acute lymphoblastic leukemia, T-ALL, though its contribution to other cancers has not been reported. To identify the taget mRNAs of CNOT3 in human non-small cell lung cancer (NSCLC), we performed the microarray analysis using A549 cells with and without knockdown against CNOT3.

ORGANISM(S): Homo sapiens

PROVIDER: GSE114694 | GEO | 2021/05/19

REPOSITORIES: GEO