SpyCLIP: An easy-to-use and high-throughput compatible platform for efficient characterization of protein-RNA interactions

ABSTRACT: We have developed a covalent linkage-based SpyCLIP method by taking advantage of SpyTag-SpyCatcher chemistry, which circumvents gel purification steps of captured RBP-RNA needed for all existing CLIP methods, thereby dramatically reducing the technical difficulty and enabling high-throughput application of the CLIP technology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE114720 | GEO | 2019/01/21

REPOSITORIES: GEO