RNAseq analysis of whole islets from pre-weaning wild type and Akita mice

ABSTRACT: This study aims to determine the effects of proinsulin misfolding/ER stress on β-cell dynamics and function in Akita mice. The RNAseq experiment offers the opportunity to investigate the impact of proinsulin misfolding/ ER stress on the genetic signature of islets isolated during the neonatal period in the Akita mice preceding the development of hyperglycemia.

ORGANISM(S): Mus musculus

PROVIDER: GSE114927 | GEO | 2018/12/02

REPOSITORIES: GEO