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Ongoing classical IL-6 signaling is required to maintain a pathogenic Th17 response in vivo

ABSTRACT: Th17 precursors from WT and IL6ra-/- mice were co-transferred into Rag1-/- mice to induce colitis. RNA was isolated from CD4+ T cells pre-transfer and from colonic CD4+ T cells 4 weeks post- transfer Another aim is to compare gene expression of WT (IL-6) v WT (HDS) v IL6RaKO (HDS) in vitro polarized Thy1.1+ Th17p cells

ORGANISM(S): Mus musculus

PROVIDER: GSE115141 | GEO | 2020/07/17

REPOSITORIES: GEO

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