Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth

ABSTRACT: We performed RNA-seq of MDA-MB-231 cells that were treated with MS645 or JQ1 at 50 nM and 500 nM in an effort to understand how MS645 exerts such a profound cell growth inhibition on cancer cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE115550 | GEO | 2018/08/31

REPOSITORIES: GEO