Heat shock-induced ribosomal intergenic spacer RNA

ABSTRACT: Cells adapt to environmental stressors such as heat shock and extracellular acidosis through formation of nuclear membrane-less compartments called Amyloid bodies (A-bodies). Stressors activate formation of Amyloid bodies (A-bodies) via induction of ribosomal intergenic spacer RNA (rIGSRNA). RNA-seq on non-ribosome depleted RNA from human MCF7 cells exposed to heat shock (43C, 30 minutes) revealed the heat shock-specific expression profile of rIGSRNA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE115731 | GEO | 2018/08/02

REPOSITORIES: GEO