Epigenetic analysis of CD8 T cells in absence of IL-10R signaling in murine tumor

ABSTRACT: ATAC-seq analysis of CD8 T cell subsets. The goal of this study was to understand the chromatin states associated to the effect of IL-10 in preventing activation-induced exhaustion of CD8+ T cells in the context of mouse tumor. The chromatin accessibility changes induced upon α-IL-10R antibody treatment in tumor-bearing mice were studied using ATACseq.

ORGANISM(S): Mus musculus

PROVIDER: GSE116389 | GEO | 2021/12/08

REPOSITORIES: GEO