Glucocorticoids enhance the anti-leukemic activity of FLT3 inhibitors in FLT3 mutant acute myeloid leukemia

ABSTRACT: Utilizing genome wide transcriptome analysis and drug screen we demonstrate that upregulation of inflammatory pathways is a key mechanism of drug tolerance to FLT3 targeted inhibitors in AML

ORGANISM(S): Homo sapiens

PROVIDER: GSE116432 | GEO | 2020/09/02

REPOSITORIES: GEO