Next Generation Sequencing of Wild Type and Nlrp6-/- T cells

ABSTRACT: Nlrp6 is expressed by T cells, but whether Nlrp6 influences the transcriptom of T cells is not known Methods: Equal numbers of Wild Type and Nlrp6-/- CD4 T cells were adoptively transfered in RAG-/- hosts, isolated from the colonic lamina propria and mRNA profiles gernerated by next generation squencing in quadruplicates using Illumina squencers. Conclusions: Our study indicates that Nlrp6 may regulate genes that are involved in apoptosis of T cells

ORGANISM(S): Mus musculus

PROVIDER: GSE116454 | GEO | 2019/05/08

REPOSITORIES: GEO