RT quantitative PCR analysis of p53 Signaling Pathway related genes in mice choclea after noise exposure.

ABSTRACT: Six month-old wild type and Igf1 heterozygous mice were exposed to a violet swept sine noise (frequency range 2–20 kHz) at 110 dB SPL for 30 minutes. Cochlear samples were taken at 2 and 24 hours post-noise exposure to study the evolution of the expression of inflammation genes by using PCR arrays and RT-qPCR. Six month-old wild type and Igf1 heterozygous mice not exposed to noise were used as control.

ORGANISM(S): Mus musculus

PROVIDER: GSE116460 | GEO | 2018/06/30

REPOSITORIES: GEO