The phosphatase regulator NIPP1 controls epidermal homeostasis

ABSTRACT: To delineate the in vivo function of NIPP1 in epidermal homeostasis, we generated skin-specific NIPP1 knockout (SKO) mice where NIPP1 is conditionally removed from keratinocytes. To gain unbiased insight into the molecular mechanism that underlies the hyperproliferation phenotype, we performed RNA-seq of the isolated epidermis of control (CTR) and SKO mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE116844 | GEO | 2020/05/14

REPOSITORIES: GEO