Joint profiling of chromatin accessibility and gene expression in thousands of single cells

ABSTRACT: Here we describe sci-CAR, a combinatorial indexing strategy to jointly profile chromatin accessibility and mRNA in each of thousands of single cells. As a proof-of-concept, we apply sci-CAR to 4,825 cells comprising a time-series of dexamethasone treatment, as well as to 11,233 cells from the mouse kidney.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE117089 | GEO | 2018/08/29

REPOSITORIES: GEO