Methylation profiling

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Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

ABSTRACT: Maternal nutrition can induce modifications in the epigenome of the fetus, resulting in gene expression alterations and impacting future performance. Epigenetic changes are related to nutrition via the one carbon cycle, which involves aminoacid methionine. We hypothesized that an increased dietary methionine in beef cows during early gestation will impact the whole-genome DNA methylation and transcriptome of the offspring.

ORGANISM(S): Bos taurus

PROVIDER: GSE117194 | GEO | 2018/07/17

REPOSITORIES: GEO

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