Genomics

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A global transcriptome analysis of human epidermal keratinocytes upon overexpression of microRNA-34a or microRNA-34c


ABSTRACT: miR-34a and miR-34c were found up-regulated at wound-edges of human venous ulcer compared to nomal wound and the intact skin; however their biological role in keratinocytes during wound repair has not been studied. To study the genes regulated by miR-34a and miR-34c, we transfected miR-34a and miR-34c mimic into human primary epidermal keratinocytes to overexpress them. We performed a global transcriptome analysis of keratinocytes upon overexpression of miR-34a or miR-34c using Affymetrix arrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117506 | GEO | 2019/09/04

REPOSITORIES: GEO

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