Molecular definition of high grade B cell lymphoma: a centroblast-like group with potential for more effective therapy

ABSTRACT: A retrospective analysis of whole transcriptome data for 928 DLBCL patients from REMoDLB clinical trial, identifies a subgroup of molecular high grade (MHG) class that present centroblast-like gene expression, enriched for MYC rearrangement, double-hit (MYC rearrangement accompanied with BCL2 and/or BCL6 rearrangement) and associated with adverse clinical outcome.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117556 | GEO | 2019/01/15

REPOSITORIES: GEO