Transcriptional profiles of [ESI+]

ABSTRACT: We profile the transcriptional landscapes associated with acquisition of [ESI+], a prion scaffolded by Snt1, a core component of the Set3C histone deacetylase. We find that acquisition of [ESI+] leads to expression of otherwise silent, heterochromatic loci, proposing a new molecular means by which silent transcriptional states might be reversed.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE117624 | GEO | 2020/02/29

REPOSITORIES: GEO