B cell single cell seq in allergen-specfic immunotherapy

ABSTRACT: IgE-producing memory cells are hard to detect in the periphery. Here, we sorted IgE+ memory B cells from allergic patients who had received allergen-immunotherapy for grass pollen. Cells were FACS-sorted and subseuqenlty sequenced by single cell RNAseq to determine isotype and phenotype. Two out of 90 cells were determiend to be true IgE producing memory B cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117803 | GEO | 2019/07/31

REPOSITORIES: GEO