ARID3a Gene Profiles are Strongly Associated with Human Interferon Alpha Production

ABSTRACT: Percentages of ARID3a-expressing low density neutrophils in SLE patients correlate with lupus disease activity and Type I IFN production. ARID3a protein levels also correlate with interferon expression in plasmacytoid dendritic cells. Gene profiles mechanistically link ARID3a with inflammatory pathway regulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117836 | GEO | 2018/09/26

REPOSITORIES: GEO