Expression data from HEK293T cells

ABSTRACT: cGAS-STING expression in HEK293T cells could up regulate a series of genes. Above them, Vpx significantly suppressed the NF-κB activated genes but had only a slight influence on the IRF3-activated genes. Diverse HIV-2 and SIV Vpx proteins showed an ability to inhibit DNA sensing-activated innate immune responses, suggesting an evolutionarily conserved function for Vpx.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117984 | GEO | 2018/08/02

REPOSITORIES: GEO