Differential expression in wild-type and mutant neurofibroma and MPNST cell lines

ABSTRACT: Using RNA-seq we characterized gene expression changes occuring upon knockout of EZH2, EZH1, EZH1+EZH2 or SUZ12 in a neurofibroma cell line. We also investigated the transcriptional consequences of EZH1+EZH2 double knockout in a SUZ12-mutant MPNST cell line.

OTHER RELATED OMICS DATASETS IN: PXD012547

ORGANISM(S): Homo sapiens

PROVIDER: GSE118185 | GEO | 2019/03/03

REPOSITORIES: GEO