Transcriptome profiles of B cell subsets from healthy and SLE subjects

ABSTRACT: SLE is characterized by the production of autoantibodies that arise from the B cell lineage. Therefore, we sought to assess the epigenetic and transcriptome profiles of distinct B cell subsets known to be expanded in SLE from healthy and SLE subjects. These data define the differentiation heirarchy of B cell subsets and the epigenetic and transcriptional consequences of SLE on human B cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE118254 | GEO | 2019/05/17

REPOSITORIES: GEO