The genomic tandem quadruplication is associated with ketoconazole resistance of Malassezia pachydermatis

ABSTRACT: Purpose: Understanding the ketoconazole resistance mechanism in Malassezia pachydermatis Methods: The transcriptome profile of the ketoconazole resistant M. pachydermatis KCTC 27587 cells compared to that of ketoconazole sensitive M. pachydermatis CBS 1879 cells were generated by RNA-Seq using Illumina HiSeq. Results: The expressions of genes in the region of quadruplicated chromosome 4 were up-regulated.

ORGANISM(S): Malassezia pachydermatis

PROVIDER: GSE118354 | GEO | 2019/02/07

REPOSITORIES: GEO