Genomics

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Effect of interferon-gamma on macrophage differentiation and response to Toll-like receptor ligands


ABSTRACT: Gene expression analysis of freshly isolated CD14+ human monocytes and monocytes cultured in the presence or absence of interferon (IFN) -gamma for 24 h and then stimulated with Pam3Cys, a Toll-like receptor (TLR) 2 ligand, for 6 h. Results provide insight into mechanisms by which IFN-gamma reprograms early macrophage differentiation and subsequent response to TLR ligands.

ORGANISM(S): Homo sapiens

PROVIDER: GSE11864 | GEO | 2008/12/31

SECONDARY ACCESSION(S): PRJNA105669

REPOSITORIES: GEO

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