Aberrant expression of interleukin-23-regulated miRNAs in T cells from patients with ankylosing spondylitis

ABSTRACT: Among the miRNAs regulated by IL-23, expression levels of 5 miRNAs were increased in T cells from patients with AS. The transfection of miR-29b-1-5p mimic could inhibit the IL-23-mediated STAT3 phosphorylation and might play a negative feedback control in the immunopathogenesis of AS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE118806 | GEO | 2018/11/28

REPOSITORIES: GEO