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C/EBPβ regulates the M2 transcriptome in β-adrenergic-stimulated macrophages

ABSTRACT: We screened RNAseq results from RAW 264.7 macrophages for previous empirically-defined M2 genes in the whole transcriptome that followed the Arg1 pattern of up-regulation by β-adrenergic-signaling with inhibition by Cebpb gene knockdown. We also screened RAW 264.7 macrophages for empirically-defined M1 genes that exhibited the orthogonal pattern of Arg1 regulation (i.e., down-regulation by β-adrenergic signaling, with rescue of this effect by Cebpb knockdown).

ORGANISM(S): Mus musculus

PROVIDER: GSE119707 | GEO | 2019/05/08

REPOSITORIES: GEO

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