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Liver gene expression profiling of cytosolic malic enzyme knockout mice

ABSTRACT: Cytosolic malic enzyme (Me1) was predicted as a causal gene for abdominal using a novel statistical method named LCMS (Schadt et al., 2005, Nature Genetics). In order to validate this prediction, we profiled the liver tissues of Me1 knockout mice (Me1-/-) and their littermate wild-type (wt) controls to examine the gene expression signature as well as pathways/networks resulting from the single gene perturbation.

ORGANISM(S): Mus musculus

PROVIDER: GSE11992 | GEO | 2009/03/08

SECONDARY ACCESSION(S): PRJNA109263

REPOSITORIES: GEO

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Liver gene expression profiling of cytosolic malic enzyme knockout mice

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