Project description:We performed gene expression profiling by Affymetrix primeview array in both NGP CRISPR control cells and NGP ALK(LF655del) cells.

2021-08-11 | GSE140025 | GEO

ChIP-seq of neuroblastoma IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5 cell lines to identify TBX2, MYCN, H3K27ac, H3K4me1 and H3K4me3 binding sites

Project description:ChIP-seq to define bindings sites for TBX2, MYCN, H3K27ac, H3K4me1, H3K4me3 and Input in the cell lines IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5.

2018-10-16 | E-MTAB-6570 | biostudies-arrayexpress

Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data

Project description:Paired End PolyA-+ RNA-sequencing of NGP cells with and without NGP treatment in 10 replicates.

2018-05-23 | GSE104756 | GEO

Transcriptome profiling of drug resistant cell lines (NGP-127).

Project description:The aim of this research was to uncover transcriptome changes in NGP-127 cells during the acquisition of resistance to anticancer drugs Sorafenib, Sunitinib, Pazopanib, Everolimus, Temsirolimus.

2017-04-14 | GSE97750 | GEO

Expression data of CFC1 overexpressed neuroblastoma cell line, NGP

Project description:We performed a microarray analysis on CFC1-expressing NGP cells. Expression data in CFC1- and mock-NGP cells were generated and compared. Differentially expressed genes (DEGs) were functionally annotated by a pathway analysis and Gene Set Enrichment Analysis (GSEA). Both analyses showed that genes involved in “differentiation”, “oncogene-induced senescence”, “stem cell proliferation” and “Activin signaling” pathways were significantly enriched in DEGs. “TGFbeta pathway” and “Nodal pathway” were also enriched in the GeneSpring GX pathway analysis, but were not significant in the GSEA analysis. This result suggests that the pathways involved in cell stemness and Activin signaling were enhanced by the expression of CFC1 in NB cells accompanied by transcriptional changes in their related gene members.

2017-12-01 | GSE90790 | GEO

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