Reprogramming the CNS of the Proto-Vertebrate Ciona intestinalis Using Single-Cell Transcriptomics

ABSTRACT: We applied single cell RNA seq with 10x genomics platform to study co-expression of both Ptf1a and Meis leading to the wholesale transformation of the entire CNS into Coronet cells. Our study identify a cocktail of regulatory determinants for the efficient specification of Coronet cells.

ORGANISM(S): Ciona intestinalis

PROVIDER: GSE120035 | GEO | 2018/09/28

REPOSITORIES: GEO