Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter

ABSTRACT: Using NGS technology we describe the transcriptomic effecs of TNFα stimulation on skeletal myogenesis and, through gene sliencing techniques, compare the effects of TNFα with the loss of a critical cell cycle regulator, Fbxl2, on the process of myogenic proliferation and differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE120600 | GEO | 2020/04/08

REPOSITORIES: GEO