Tumor-infiltrating immune cells of young and aged mice

ABSTRACT: Macrophages, dendritic cells, conventional CD4+ T cells, CD8+ T cells, and regulatory T cells isolated from mouse colon cancer model MC38 tumors implanted subcutaneously to young (3 month) and aged (12 month) mice were sequenced using ImmGen's standard ultra-low input RNA-seq pipeline, in order to study age-dependent differences in intraltumoral immune cell functions and their impact on tumor control

ORGANISM(S): Mus musculus

PROVIDER: GSE121075 | GEO | 2018/11/01

REPOSITORIES: GEO