SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors

ABSTRACT: We performed RNA sequencing analysis using NextSeq500 to identify drivers that mediate feedback RAS activation in BRAF(V600E) cells that are SHP2 independent.

ORGANISM(S): Homo sapiens

PROVIDER: GSE121117 | GEO | 2018/10/12

REPOSITORIES: GEO