Gene expression in basal progenitors in the cerebral cortex of Tbr2 conditional knockout mice

ABSTRACT: During cortical development neurons are generated from basal progenitors (BPs) which specifically express the transcription factor Tbr2. We used fluorescent-activated cell sorting (FACS) to isolate BPs from Tbr2-conditional knockout mice brain at early (E13) and late (E16) stages of cortical neurogenesis and determined mRNA expression profiles using microarray (Illumina MouseWG-6 v2). Role of transcription factor Tbr2 in basal progenitors during corticogenesis.

ORGANISM(S): Mus musculus

PROVIDER: GSE121180 | GEO | 2019/10/12

REPOSITORIES: GEO