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Expression data upon treatment of human mesothelioma mouse model with nucleolin-targeted nanoparticle (PEGASEMP)

ABSTRACT: The goal of this study was to identify transcriptome alterations behind the antitumor effect of PEGASEMP, a liposomal formulation of doxorubicin targeted by the nucleolin-binding F3 peptide, and hence infer on the mechanism of action. It was used microarray technology to assess the gene expression alterations upon treatment of a human biphasic mesothelioma orthotopic mouse model (aggressive disease subtype) with PEGASEMP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE121205 | GEO | 2021/02/16

REPOSITORIES: GEO

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Expression data upon treatment of human mesothelioma mouse model with nucleolin-targeted nanoparticle (PEGASEMP)

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