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RNAseq on developmental endoreplicating (salivary glands) cells in Drosophila melanogaster

ABSTRACT: In order to evaluate the global transcriptomic changes in endoreplicating cells in Drosophila melanogaster we performed RNA-Seq. Endoreplicating cells (salivary glands) and mitotic cycling cells (brains and imaginal discs) were harvested from feeding 3rd instar larvae and mRNA levels were compared. Consistent with our previous results, we found that endoreplicating cells repress genes regulated by the E2F1 transcription factor as well as genes regulated by the Myb-MuvB (MMB) transcription factor complex.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE121956 | GEO | 2019/06/22

REPOSITORIES: GEO

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