Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiR-Seq on paired skin and oral mucosal wound healing

ABSTRACT: To delineate the role of microRNAs in the site-specific injury response, we compared the microRNAome of skin and oral mucosa both at baseline and throughout the time course of wound healing.

ORGANISM(S): Mus musculus

PROVIDER: GSE121996 | GEO | 2019/05/29

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional profiling of a wound healing process in skin and oral mucosa

Project description:When compared to skin, oral mucosal wounds heal rapidly and with reduced scar formation. This study used an Affymetrix microarray platform to compare the transcriptomes of oral mucosa and skin wounds in order to identify critical differences in the healing response at these two sites. Using microarrays, we explored the differences in gene expression in skin and oral mucosal wound healing in a murine model of paired equivalent-sized wounds. Samples were examined from day 0 to day 10 and spanned all stages of the wound healing process. Unwounded matched tissue was used as a control. Tissue samples collected at each post-wounding time point, as well as control samples, were represented by 3 biological replicates.

2010-07-20 | E-GEOD-23006 | biostudies-arrayexpress

miR-Seq on paired skin and oral mucosal wound healing

Project description:miR-Seq on paired skin and oral mucosal wound healing

| PRJNA501906 | ENA

Human Oral and Cutaneous Wound Healing Transcriptomes

Project description:Comparative analysis between oral and cutaneous wound healing in humans using paired and sequential biopsies during the repair process.

2018-08-07 | GSE97615 | GEO

Mouse wound healing [RNA-seq]

Project description:Mouse wound healing [RNA-seq]

| PRJNA526702 | ENA

Gene expression in human oral mucosal fibroblasts and patient-matched skin fibroblasts

2011-01-01 | GSE21648 | GEO

Gene expression in human oral mucosal fibroblasts and patient-matched skin fibroblasts

Project description:Wound healing within the oral mucosa results in minimal scar formation compared to wounds within the skin. We have recently demonstrated distinct differences in the ageing profiles of cells (oral mucosal and patient-matched skin fibroblasts) isolated from these tissues. We hypothesize that the increased replicative potential of oral mucosal fibroblasts may confer upon them preferential wound healing capacities. Passage-matched early cultures of oral mucosal fibroblasts and skin fibroblasts demonstrated distinct gene expression profiles with a number of genes linked to wound healing/tissue repair. We analyzed the gene expression profiles of oral mucosal and patient-matched skin fibroblasts for multiple patients both prior to (0h) and (6h) following a wounding stimulus. Differences in the gene expression profiles of oral mucosal and patient-matched skin fibroblasts were anlazyed for multiple patients both prior to (0h) and (6h) following a wounding stimulus. Serum starvation and subsequent stimulation provides a model for wounding and RNA extracted at 0h and 6h following this stimulus was hybridized to Affymetrix microarrays for analysis. We sought to compare the expression profiles both between oral and normal fibroblasts, in both serum depleted and stimulated conditions and also compare differences between patients.

2011-01-01 | E-GEOD-21648 | biostudies-arrayexpress

MicroRNA array expression during normal urinary bladder wound healing

Project description:Urinary bladder wound healing is today pooorly chracterized. MicroRNAs are small non-coding RNA molecules with regulatory functions. In this study we aimed at identifying microRNAs expressed during bladder wound healing. We performed Affymetrix microRNA profiling of the rodent urinary bladder during healing of a surgically created wound.

2021-12-01 | GSE176515 | GEO

Calcareous Sponge Sycon Ciliatum Wound Healing

Project description:S.ciliatum wound healing - transcriptome sequencing

| PRJEB49227 | ENA

Transcriptional profiling of a wound healing process in skin and oral mucosa

2010-07-20 | GSE23006 | GEO

Oral mucosal host-microbiome model

Project description:Development of an oral mucosa model to study host-microbiome interactions during wound healing

| PRJEB5215 | ENA