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Exon Level Expression Profiling: a Novel Unbiased Transcriptome

ABSTRACT: Transcriptome analysis of partially degraded and fragmented RNA samples from hiPSCs-derived MNs with Venus or Fos-B + Venus expression by lentivirus infection Fos-B could had a function on axon branching with hiPSCs-derived MNs. However, the grobal profiling under Fos-B expression was not fully elucidated. Thus, we constructed Venus or Fos-B + Venus expression lentivirus and subsequently infected those virus to hiPSCs-derived MNs. Increasing number of axon branching was detected with Fos-B expression MNs, and we demonstrated the pathological confirmation of true exon level expression profiling approach with Fos-B expressed MNs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE122010 | GEO | 2019/08/07

REPOSITORIES: GEO

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IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated Amyotrophic Lateral Sclerosis

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2013-04-16 | E-GEOD-45191 | biostudies-arrayexpress

Expression data from embryonic mouse cervical spinal cords

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Gene expression data from cultured mouse cortical (mCTX) neurons in different stimulation and knockdown conditions

2014-09-07 | GSE60049 | GEO

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