Genomics

Dataset Information

0

Dysfunction and stemness of tumor-infiltrating T cells are triggered by a common mechanism


ABSTRACT: The paradox of tumor immunology is that tumor infiltrating lymphocytes (TILs) are dysfunctional in situ and yet are capable of stem cell-like behavior with self-renewal, massive expansion, multipotency, and eradication of large metastatic tumors. Here we report that the overabundance of potassium in the tumor microenvironment (TME) can explain both phenomena.

ORGANISM(S): Mus musculus

PROVIDER: GSE122156 | GEO | 2019/04/03

REPOSITORIES: GEO

Similar Datasets

2023-12-29 | E-MTAB-12910 | biostudies-arrayexpress
2024-03-15 | PXD045710 | Pride
2013-12-31 | E-GEOD-42824 | biostudies-arrayexpress
2023-01-01 | GSE221534 | GEO
2023-01-01 | GSE221533 | GEO
2021-01-13 | GSE164153 | GEO
2024-02-14 | PXD031794 | Pride
2021-03-30 | PXD014383 | Pride
2019-12-04 | GSE136094 | GEO
2023-08-23 | GSE221590 | GEO