Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance

ABSTRACT: To Study the role of mutant Braf V600E and ERK dependent phosphorylation of TFEB in regulation of autophagy and lysosome biogenesis in the context of melanoma growth and metastasis, we used whole geneome RNA-seq to study role TFEB mediated BRAFV600E autophagy regulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE122614 | GEO | 2019/03/21

REPOSITORIES: GEO