RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells

ABSTRACT: We found that CDK11 KD in hESCs caused hESC differentiation. To get the detailed mechanism why its KD caused differentiation, we applied RNA-seq analysis, aiming to find out some clues about the mechanism. Firstly, we obtained the differentially expressed genes (DEGs) from NC and CDK11 KD hESC cells, replicated NC and 2 sets of CDK11 siRNA were transfected into SHhES8 cells for 4 days. Later, we analyzed the data and used GO analysis to enrich GO terms which might be helpful for our research.

ORGANISM(S): Homo sapiens

PROVIDER: GSE123410 | GEO | 2018/12/07

REPOSITORIES: GEO