Small molecule inhibitor of PRC1 E3 ligase activity induces differentiation of leukemia initiating cells [RNA-Seq]

ABSTRACT: We have developed small molecule inhibitors of PRC1. These inhibitors target PRC1, decrease H2A ubiquitination and differentiation of TEX cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE123490 | GEO | 2021/04/06

REPOSITORIES: GEO