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Expression data of butyrate stimulated epithelial organoid cultures generated from intestinal mucosa

ABSTRACT: In order to investigate the response of epithelium to butyrate, we generated in vitro epithelial organoid cultures from colon samples of non-IBD controls and they were stimulated with different doses of butyrate. The transcriptional signature revealed that butyrate negatively regulated proliferation and cell cycle, induced a protective response to oxidative stress and regulated genes related to the immune response.

ORGANISM(S): Homo sapiens

PROVIDER: GSE123553 | GEO | 2019/06/12

REPOSITORIES: GEO

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