Genomics,Multiomics

Dataset Information

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Genome-wide analysis of histone H3 acetylation levels of wild type, hda6, hdc1, and hda19 in short day conditions [ChIP-seq]


ABSTRACT: To investigate whether the expression of upregulated genes in hdc1 and hda19 is assoiated with histone acetylation levels increased in the hdc1 and hda19 mutants, We carried out ChIP-seq to examine histone H3 acetylation at the whole-genome level. Overall design: Examination of histone H3 acetylation levels in 4 samples.

INSTRUMENT(S): Illumina HiSeq 2500 (Arabidopsis thaliana)

ORGANISM(S): Arabidopsis thaliana  

SUBMITTER: xinjian He  

PROVIDER: GSE124414 | GEO | 2018-12-28

REPOSITORIES: GEO

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Publications

The HDA19 histone deacetylase complex is involved in the regulation of flowering time in a photoperiod-dependent manner.

Ning Yong-Qiang YQ   Chen Qing Q   Lin Rong-Nan RN   Li Yong-Qiang YQ   Li Lin L   Chen She S   He Xin-Jian XJ  

The Plant journal : for cell and molecular biology 20190303 3


Chromatin modifications are known to affect flowering time in plants, but little is known about how these modifications regulate flowering time in response to environmental signals like photoperiod. In Arabidopsis thaliana, HDC1, a conserved subunit of the RPD3-like histone deacetylase (HDAC) complex, was previously reported to regulate flowering time via the same mechanism as does the HDAC HDA6. Here, we demonstrate that HDC1, SNLs and MSI1 are shared subunits of the HDA6 and HDA19 HDAC complex  ...[more]

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