Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling

ABSTRACT: We have performed RNAseq analysis of human T cells upon PPP1R11 siRNA silencing. We have explored the role of PPP1R11 for the first time in primary human T cells and discovered that PPP1R11 is a novel negative mediator of T cell activation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE124757 | GEO | 2019/03/08

REPOSITORIES: GEO